Disseminated intravascular coagulation in dogs with gastric dilatation-volvulus syndrome
نویسندگان
چکیده
Gastric dilatation and volvulus syndrome is associated with changes in haemostatic profiles. The aims of this study were to compare selected haemostatic and fibrinolytic parameters between healthy dogs and dogs with gastric dilatation and volvulus syndrome, estimate the incidence of disseminated intravascular coagulation (DIC), and determine the most sensitive test for detection of DIC in these patients. Blood was collected from 22 dogs with gastric dilatation and volvulus syndrome, and nine healthy control dogs. Platelet counts, prothrombin time, activated partial thromboplastin time, fibrinogen concentrations and fibrin/fibrinogen degradation products were measured in all control dogs and patients with gastric dilatation and volvulus syndrome, before and after surgery. Significant differences between control dogs and patients were seen in activated partial thromboplastin time and fibrin/fibrinogen degradation products before surgery and all measured parameters after surgery. The incidence of DIC was 59%. The most sensitive tests for detection of DIC before surgery were those for activated partial thromboplastin time and fibrin/fibrinogen degradation products.
منابع مشابه
Laparoscopic-assisted and laparoscopic prophylactic gastropexy: indications and techniques.
Gastric dilatation–volvulus (GDV) is a syndrome characterized by rapid accumulation of gas or food in the stomach, increased intragastric pressure and wall tension, and rotation of the stomach about its long axis. Gastric distention unleashes a series of potentially lethal pathophysiologic events, the most important of which are compression of the portal and caudal vena caval venous blood flow,...
متن کاملGastric Dilatation-volvulus: Lactate Clearance and Prognosis
Gastric dilatation-volvulus is an acute life-threatening condition that primarily affects large-breed dogs. By definition, the initiating event of the syndrome involves an abnormal entrapment and accumulation of fluid and air within the gastric lumen that results in extreme, traumatic distention of the stomach (dilatation) and variable rotation of the stomach on its long axis (volvulus). Early ...
متن کاملAcute idiopathic gastric dilation with gastric necrosis in individuals with Prader-Willi syndrome.
Individuals with Prader-Willi syndrome (PWS) have excessive appetite with the ability to consume large quantities of food. Absence of vomiting and a high pain threshold are considered manifestations of the disorder. We present 6 patients with PWS with acute dramatic gastric distention. In 3 young adult women with vomiting and apparent gastroenteritis, clinical course progressed rapidly to massi...
متن کاملDisseminated Intravascular Coagulation in a Case of Brucellosis Misdiagnosed as Thrombotic Thrombocytopenia Purpura
متن کامل
Defibrination syndrome due to scorpion venom poisoning.
Disseminated intravascular coagulation occurred in dogs given scorpion venom subcutaneously in doses of 3 mg./kg. body weight. Treatment with heparin reversed the coagulation abnormality of the syndrome and 10 out of 12 dogs survived. Necropsy findings in human patients stung by scorpions suggest that this syndrome also occurs in man.
متن کامل